Bills beat Lions 41-31 in Highmark Stadium opener; Josh Allen accounts for five TDs

Buffalo opened its new stadium with a primetime win as Josh Allen delivered a five-touchdown performance and the team improved to 2-0.

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- Final score: Bills 41, Lions 31.
- Buffalo improved to 2-0; Detroit fell to 1-1.
- Josh Allen: 20-of-31, 248 passing yards, 3 pass TDs; 69 rushing yards, 2 rushing TDs.
- James Cook: 101+ rushing yards (game reporting varies between 101–135 in outlets); Dalton Kincaid: team-high receiving yards and a touchdown.
- Bills outgained Lions and produced 446 total yards (team source).
- Joe Brady begins his Bills tenure 2-0 as head coach (team report).
- Allen's two-game start (through Week 2) features multiple multi-TD performances, energizing Buffalo's offense.
- The team opened Highmark Stadium with a marquee victory that sets a positive early-season tone.

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